Wegovy Side Effects at 2.4 mg — What the Label Says Lasts
Wegovy side effects at the 2.4 mg maintenance dose — stomach symptoms, fatigue, hair loss, skin sensations, gallbladder and heart rate — from the FDA label.
Worth remembering
- At 2.4 mg, the label's most common side effects are nausea (44%), diarrhea (30%), vomiting (24%) and constipation (24%).
- Fatigue, headache, dizziness, hair loss and changes in skin sensation are also on the list.
- Gallstones were more common on Wegovy than placebo in the label's weight-management trials.
- The label says Wegovy can raise resting heart rate and asks you to report a racing heart that lasts several minutes.
- If a dose isn't tolerated, the label lets your prescriber delay the next step or choose 1.7 mg for maintenance.
You made it through the climb. Four months of step-ups, a few rough weeks at 1.7 mg, and now you're on 2.4 mg, the dose the label recommends for long-term weight management. The nausea is quieter. But you're more tired than you expected, your hairbrush seems fuller, and you're wondering which of these are Wegovy and which are just life.
Most side-effect guides focus on week one. This one looks at what the Wegovy label says about the maintenance dose. Its weight-management trials ran for up to 68 weeks, so the numbers below describe more than a first impression.
What are the most common side effects at 2.4 mg?
The label pools three placebo-controlled trials of adults with obesity or overweight treated with Wegovy 2.4 mg for up to 68 weeks. These are the side effects reported by at least 5% of people on Wegovy, and more often than on placebo:
| Side effect | Placebo | Wegovy 2.4 mg |
|---|---|---|
| Nausea | 16% | 44% |
| Diarrhea | 16% | 30% |
| Vomiting | 6% | 24% |
| Constipation | 11% | 24% |
| Stomach pain | 10% | 20% |
| Headache | 10% | 14% |
| Fatigue | 5% | 11% |
| Indigestion | 3% | 9% |
| Dizziness | 4% | 8% |
| Bloating | 5% | 7% |
| Burping | <1% | 7% |
| Gas | 4% | 6% |
| Stomach flu (gastroenteritis) | 4% | 6% |
| Reflux | 3% | 5% |
Further down the list are gastritis (4%), hair loss (3%) and dysesthesia (2%). For people with type 2 diabetes in these trials, low blood sugar was reported by 6% on Wegovy versus 2% on placebo.
In these trials, 6.8% of people on Wegovy stopped because of side effects, compared with 3.2% on placebo. The most common reasons were nausea, vomiting and diarrhea.
Why might I feel tired or dizzy?
Fatigue (11%) and dizziness (8%) are both in the label's table. The label doesn't explain the cause. It's worth noticing whether they track with eating less, drinking less or a run of stomach symptoms. The label links vomiting and diarrhea to dehydration, which in turn can lead to kidney problems.
Is the hair loss real?
It is in the label. 3% of adults on Wegovy 2.4 mg reported hair loss, compared with 1% on placebo. At the higher 7.2 mg dose, which the current label allows for some adults, it was 6%. The label doesn't say how long it lasts or whether it reverses. If it's worrying you, it's a fair thing to raise at your next appointment.
What's this about skin feeling strange?
The label calls it dysesthesia. It's a group term covering tingling, burning, extra-sensitive skin or skin pain without an obvious cause. At 2.4 mg it was uncommon (2%). At 7.2 mg it was reported by 22% of people. If your prescriber ever discusses the higher dose, this is one of the differences the label highlights.
What about my gallbladder and heart rate?
Two less common effects get their own sections in the label:
- Gallbladder. In the weight-management trials, gallstones were reported by 1.6% of adults on Wegovy injection versus 0.7% on placebo, and gallbladder inflammation by 0.6% versus 0.2%. Some gallbladder problems need surgery.
- Heart rate. The label says Wegovy can raise your resting heart rate, and that your provider should check it during treatment. The Medication Guide asks you to report a racing or pounding heart that lasts several minutes.
The label also covers pancreatitis, serious allergic reactions, vision changes in people with type 2 diabetes, and the risk of food or liquid entering the lungs during anesthesia. That last one is why you should tell anyone doing a procedure that you're on Wegovy. Its boxed warning concerns thyroid C-cell tumors seen in rodents, and Wegovy isn't used in people with a personal or family history of medullary thyroid carcinoma or MEN 2.
If side effects are hard to live with, what are the options?
The label gives your prescriber room. If a step isn't tolerated, they can consider delaying the next increase by four weeks. For weight reduction in adults, 1.7 mg is also a listed maintenance dose, and the label says to weigh tolerability when choosing. Those are decisions to make with your prescriber, not by skipping or splitting doses yourself.
What we'd track
On the maintenance dose, side effects tend to become patterns rather than events. These are the things we'd log to make those patterns visible:
- Shot day and dose. Every symptom is easier to read with the dose day next to it.
- Stomach symptoms, by day after the shot. If nausea always lands on day two, that's useful to know.
- Energy and dizziness. A quick daily rating is enough to show a trend.
- Water intake. Especially on days with vomiting or diarrhea.
- Anything new. Hair shedding, skin sensations or a racing heart, dated and described in a few words.
Holt lines up side effects against your dose days, tracks water and weight trends, and builds a doctor-visit report so the conversation about 1.7 mg versus 2.4 mg starts from facts.
Track Wegovy side effects against your shot daysFor the weekly routine and the missed-dose rules, see our Wegovy tracker.
See it in Holt
Real screens from the app — the same places you’ll log, review and share.
Side effects, by severity 
Medication level and next dose 
A report for your next appointment
Frequently asked questions
Do Wegovy side effects go away once you reach 2.4 mg?
The label doesn't say how long they last for any one person. Its weight-management trials ran up to 68 weeks, so the rates it reports cover time on the maintenance dose, not just the start. Tell your prescriber if a side effect isn't easing.
Does Wegovy cause hair loss?
Hair loss was reported by 3% of adults on Wegovy 2.4 mg versus 1% on placebo in the label's trials, and by 6% at 7.2 mg. The label doesn't say whether it reverses.
Why does my skin feel strange or tingly on Wegovy?
The label lists dysesthesia — tingling, burning, extra sensitivity or pain of the skin — in 2% of adults on 2.4 mg and 22% on 7.2 mg. Mention it to your prescriber, especially if it's bothering you.
Is 1.7 mg an option if 2.4 mg is too much?
Yes. For weight reduction in adults, the label lists both 1.7 mg and 2.4 mg as maintenance doses and says to consider tolerability when choosing. Only your prescriber can make that change.
Sources
- WEGOVY (semaglutide) injection and tablets — Prescribing Information and Medication Guide (revised 06/2026) — U.S. Food and Drug Administration
- WEGOVY (semaglutide) injection — Prescribing Information (2025) — U.S. Food and Drug Administration
Keep reading
- Wegovy TrackerA calm way to track weekly Wegovy injections, the 4-week dose steps, injection sites and how you feel, with the label's missed-dose rules in plain words.
- Ozempic Side EffectsWhat the Ozempic label says about side effects in type 2 diabetes — stomach symptoms by dose, low blood sugar with insulin or sulfonylureas, eyes, and when to call.
- Wegovy vs ZepboundWegovy vs Zepbound for weight management — how their approvals, dose schedules, pens, vials and tablets differ, and what the SURMOUNT-5 head-to-head trial found.
- GLP-1 Side EffectsThe most common GLP-1 side effects for semaglutide and tirzepatide, when they tend to appear, which warning signs need a doctor, and how tracking helps.